Meyer-Overton rule

Mey·er-O·ver·ton rule

(mī'ĕr ō'vĕr-tŏn),
because inhalation agents act through the lipid-rich CNS cells, anesthetic potency increases with lipid solubility.

Meyer,

Hans H., German pharmacologist, 1853-1939.
Meyer-Overton rule - because inhalation agents act through the central nervous system cells, anesthetic potency increases with lipid solubility.
Meyer-Overton theory of narcosis - that narcotic efficiency parallels the coefficient of partition between oil and water, and that lipoids in the cell and on the cell membrane absorb the drug because of this affinity. Synonym(s): lipoid theory of narcosis

Overton,

Charles E., German biologist in Sweden, 1865-1933.
Meyer-Overton rule - see under Meyer, Hans H
Meyer-Overton theory of narcosis - see under Meyer, Hans H