methylglyoxal

(redirected from Methyl glyoxal)

meth·yl·gly·ox·al

(meth'il-glī-ok'săl),
Pyruvaldehyde; the aldehyde of pyruvic acid; an intermediate of carbohydrate metabolism in certain organisms.
Synonym(s): pyruvic aldehyde

methylglyoxal

(mĕth″ĭl-glī-ŏk′sĭl, -awl)
An aldehyde formed from the metabolic degradation of glucose. Methylglyoxal can bind to proteins and DNA, causing metabolic damage to tissues (e.g., in diabetes mellitus), mutations, or cell death.
References in periodicals archive ?
Antibacterial constituents and mechanisms identified include hydrogen peroxide (H2O2), methyl glyoxal (MGO), bee defensin-1, the osmotic effect, and pH effects.
Antibacterial properties of honey are the result of the low water activity causing osmosis, chelation of free iron, its slow release of hydrogen peroxide, high acidity, and the antibacterial activity of methyl glyoxal.
For the determination of the ability of the candidate compounds to inhibit the methyl glyoxal (MGO) this test was used, and examine the development of fluorescence of Bovine serum albumin (BSA).
An aromatic component (Diacetyl) is one of the identified mutagens, as is the closely related methyl glyoxal, which is highly mutagenic in bacteria,
Preliminary evidence indicates that methyl glyoxal is a carcinogen in injection tests in rats.
This may result in their failure to form acetal linkage with methyl glyoxal.