This first volume in the series focuses on quinine methides
Considering that quinone methides
are the resonance hybrids between the quinoid and benzenoid structures, and their high reactivity to electrophiles and nucleophiles, it is evident that the polycondensation mechanism in all catalytic conditions can be explained by their participation.
The resol type phenolic resin prepared by the reaction of phenol and formaldehyde in alkaline conditions comprised complicated mixtures of mono- or polynuclear hydroxymethyl phenols (6, 7) and para-quinone methides
Figueiredo JN, Raz B, Sequin U (1998) Novel quinone methides
from Salacia kraussii with in vitro antimalarial activity.
Phenolic resin prepared by the reaction of phenols and formaldehyde under alkaline conditions comprises complicated mixtures of mononuclear or polynuclear hydroxymethyl phenols (9, 10) and para-quinone methides