metalloproteinase


Also found in: Dictionary, Wikipedia.

me·tal·lo·pro·tein·ase

(met'a-lō-prō'tēn-āz),
A family of protein-hydrolyzing endopeptidases that contain zinc ions as part of the active structure.

me·tal·lo·pro·tein·ase

(mĕ-tal'ō-prō'tēn-ās)
A family of protein-hydrolyzing endopeptidases that contain zinc ions as part of the active structure.
References in periodicals archive ?
With transformation from benign to malignant condition, and with increasing histologic grade the expression of matrix metalloproteinase is increased.
General overview of extracellular matrix metalloproteinase structure is given in Figure 1 [18].
Time-course changes in mesenteric collagen type I, matrix metalloproteinase-2, membrane type 1-matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 protein expression after ovariectomy
Among those who received MK-7, disease activity score, erythrocyte sedimentation rate, serum undercarboxylated osteocalcin, C-reactive protein, and matrix metalloproteinase decreased significantly from baseline levels.
Effects of conjugated linoleic acids and docosahexaenoic acid on rat liver and reproductive tissue fatty acids, prostaglandins and matrix metalloproteinase production.
Overall, "Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo," Blood, vol.
Libert, "Is there new hope for therapeutic matrix metalloproteinase inhibition?
37, 38] Studies have shown that increased monocyte activation and differentiation activated macrophages that can further induce inflammatory cytokines, resulting in increased activation and expression of matrix metalloproteinase (MMPs), particularly MMP-9.
ADAM family proteinases (a disintegrin and metalloproteinase) and ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) are also associated, being involved in a large spectrum of activities, such as fertilization, development, and carcinogenesis [29].
Expression of matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP1) by colorectal cancer cells and adjacent stroma cells-associations with histopathology and patients outcome.

Full browser ?