sepsis syndrome

(redirected from Metabolic derangement)

sepsis syndrome

clinical evidence of acute infection with hyperthermia or hypothermia, tachycardia, tachypnea and evidence of inadequate organ function or perfusion manifested by at least one of the following: altered mental status, hypoxemia, acidosis, oliguria, or disseminated intravascular coagulation.

sepsis syndrome

clinical evidence of acute infection with hyperthermia or hypothermia, tachycardia, tachypnea and evidence of inadequate organ function or perfusion manifested by at least one of the following: altered mental status, hypoxemia, acidosis, oliguria, or disseminated intravascular coagulation.

sepsis syndrome

A constellation of signs, Sx, and systemic responses caused by a wide range of microorganisms that may eventuate into septic shock; SS is a systemic response to infection
Sepsis syndrome, defining parameters  
• Temperature Hypothermia < 35ºC–96ºF or hyperthermia > 39ºC–101ºF
• Tachycardia > 90 beats/minute
• Tachypnea > 20 breaths/minute
• Site of infection Clinically evident focus of infection or positive blood cultures
• Organ dysfunction 1+ end organs with either dysfunction or inadequate perfusion or cerebral dysfunction
• Metabolic derangement Hypoxia–PaO2 < 75 mm Hg, ↑ plasma lactate/unexplained metabolic acidosis
• Fluid imbalance Oliguria–< 30 mL/hr
• WBC counts < 2.0 x 109/L; > 12.0 x 109/L–US: < 2000/mm3; > 12 000/mm3
Note: The confusing semantics of the terms sepsis, sepsis/septic syndrome, and septic shock are unlikely to be resolved in the forseeable future; the terms sepsis and septic syndrome are essentially interchangeable and would in part overlap with septicemia–the early components of a pernicious infectious cascade that has spilled into the circulation; the term septic shock is used when the process becomes virtually irreversible.

sep·sis syn·drome

(sep'sis sin'drōm)
Clinical evidence of acute infection with hyperthermia or hypothermia, tachycardia, tachypnea, and evidence of inadequate organ function or perfusion manifested by at least one of the following: altered mental status, hypoxemia, acidosis, oliguria, or disseminated intravascular coagulation.

sep·sis syn·drome

(sep'sis sin'drōm)
Clinical evidence of acute infection with hyperthermia or hypothermia, tachycardia, tachypnea, and evidence of inadequate organ function.
References in periodicals archive ?
About 10% were taking a medication with a high risk of metabolic derangement (clozapine, olanzapine).
The software calculates rates for three PSIs (Postoperative Hemorrhage or Hematoma, Physiologic and Metabolic Derangement, and Respiratory Failure); however, as they were not officially endorsed by the NQF at the time the composite was developed, it excludes them from the composite by assigning them zero weights.
While cardiovascular conditions and diabetes are commonly linked to obesity (which may be lifestyle induced), a recent study suggests that the correlation between a disadvantageous fetal environment and metabolic derangement may stand regardless of whether a child becomes overweight (Bush 2011).
Observational studies have identified repeated and prolonged seizures, intracranial hypertension, severe metabolic derangement, deep and prolonged coma as risk factors for poor outcome (8).
001908 Postoperative physiologic & metabolic derangement .
of Ulster-Coleraine) describes recent research into the role of bioactive peptides in addressing the metabolic derangement and nutritional deficits that contribute to unwanted weight loss in response to infection, injury, or chronic disease.
He was not in control of his actions at the time due to metabolic derangement, in particular hypoglycaemia as well as dehydration.
To exclude pyroglutamic acidosis as a cause of the metabolic derangement, a urine sample was sent for organic acid analysis by GC-MS (4).
On presentation she was placed on continuous haemodiafiltration for renal failure and significant metabolic derangement.
21) The immediate question is whether this metabolic derangement is characteristic of TB pathophysiology, or whether people with this derangement are prone to TB.
5) The endpoint here, of course, is to rapidly triage patients with a metabolic derangement in the hopes of decreasing the severity of their illness and, ultimately, the duration and cost of their hospitalization.
This enzymatic deficiency leads to severe metabolic derangement, manifested clinically as vomiting, dehydration, and acidosis progressing to seizures, coma, and death.