TPN

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Related to Metabolic defects: Birth defects, Inborn errors of metabolism

TPN

 

TPN

Abbreviation for total parenteral nutrition.

TPN

total parenteral nutrition.

TPN

abbr.
total parenteral nutrition

TPN

abbreviation for total parenteral nutrition.

TPN

Total parenteral nutrition IV hyperalimentation Critical care A modality that attempts to provide all the body's need for nutrition without using the GI tract Indications
1. Correction of nutritional depletion in the face of inadequate oral intake and/or intestinal absorption, as in Crohn's disease, malignancy, pseudo-obstruction, radiation enteritis, short bowel syndrome, sprue and.
2. Conditions requiring bowel rest and nutritional restitution–eg, nonspecific colitides and associated growth retardation, enterocutaneous fistulas and pancreatitis TPN is used for children with diaphragmatic hernia, malrotation, esophageal atresia, tracheoesophageal fistula, gastroschisis, volvulus, meconium ileus and omphalocele; severely malnourished See Cancer cachexia. Cf Enteral nutrition.
Complications of TPN
Hepatic dysfunction Cholestasis, cholelithiasis, hepatic dysfunction, jaundice, hepatomegaly, micronodular cirrhosis, lipofuscinosis and steatosis–most common in premature infants
Related to indwelling IV line Misplacement of line, infections, eg Candida spp, aspergillosis
Metabolic defects Hyperglycemia–osmotic diuresis, hyperosmolarity, post-infusion hypoglycemia, hyperosmolar coma, ketoacidosis and other metabolic derangements, excess or deficiency of electrolytes, including Na+, K+, Cl, eg hyperchloremic acidosis and mineral imbalances, affecting Mg2+, PO4, and Ca2+ with hypercalcemia and accompanying pancreatitis, hypercalciuria and metabolic bone disease
Nutritional imbalances Generalized ↓ in essential fatty acids, trace minerals–copper, chromium, molybdenum, tin, zinc, and vitamins and ↑ TGs, cholesterol
.

TPN

Abbreviation for three-in-one total parenteral nutrition; total parenteral nutrition; triphosphopyridine nucleotide.

Total parenteral nutrition (TPN)

A solution containing all the required nutrients including protein, fat, calories, vitamins, and minerals, is injected over the course of several hours, into a vein. TPN provides a complete and balanced source of nutrients for patients who cannot consume a normal diet.

TPN

Abbreviation for total parenteral nutrition.

TPN

total parenteral nutrition; see parenteral nutrition.

Patient discussion about TPN

Q. why is it that some women lack parental nutrition?

A. Do you mean breastfeeding? Some women have problem with their nipples, in rare cases the breast tissue isn't developed enough. Sometimes breast surgeries damage the milk ducts. Psychological factors also play a role.

More discussions about TPN
References in periodicals archive ?
AntiCancer is also developing new cancer drugs based on genetic engineering that target cancer-specific metabolic defects.
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Instead of addressing amyloid or tau, AC-1204 addresses the metabolic defects seen in the disease," added Samuel Henderson, Ph.
The study has a total planned enrollment of approximately 480 patients and is the first of two Phase 3 trials of AC-1204, an investigational new drug designed to address the metabolic defect of the brain observed in Alzheimer's patients.
In the study, the researchers used a high-resolution variant of fMRI to map metabolic defects in the brains of 96 adults enrolled in the Washington Heights-Inwood Columbia Aging Project (WHICAP).
The observed differences in therapeutic effectiveness and safety validate the strategy of initial triple therapy, namely, that it's better to target the insulin resistance and progressive beta-cell failure that constitute the core metabolic defects responsible for hyperglycemia and type 2 diabetes instead of simply focusing on lowering plasma glucose, added Dr.
Researchers from the University of Leicester Departments of Health Sciences and Cardiovascular Sciences revealed that women who are sedentary for most of the day were at a greater risk from exhibiting the early metabolic defects that act as a precursor to developing type 2 diabetes than people who tend to sit less.
In states of obesity, the production profile of these adipokines is altered to one that promotes low-grade systemic inflammation, contributing to the metabolic defects underlying type 2 diabetes, hypertension, and cardiovascular diseases.
Axona targets the metabolic defects of glucose utilization in the brain by providing an alternative energy source.
12) It has been suggested that hyperandrogenemia plays a direct role in the development of associated metabolic abnormalities in female relatives of PCOS women (9,13); these data together with familial clustering of PCOS suggest that male relatives of PCOS women may develop similar metabolic defects and hence may be at increased risk of CVD.