Merkel cell tumor

Mer·kel cell tu·mor

a rare malignant cutaneous tumor seen in sun-exposed skin of elderly patients composed of dermal nodules of small round cells with scanty cytoplasm in a trabecular pattern; the tumor cells contain cytoplasmic dense core granules resembling neurosecretory granules seen in Merkel cells.


Friedrich Sigmund, German anatomist and physiologist, 1845-1919.
Merkel cell tumor - a rare malignant cutaneous tumor. Synonym(s): primary neuroendocrine carcinoma of the skin; trabecular carcinoma
Merkel corpuscle - a specialized tactile sensory nerve ending in the epidermis. Synonym(s): Merkel tactile cell; Merkel tactile disk; tactile meniscus
Merkel tactile cell - Synonym(s): Merkel corpuscle
Merkel tactile disk - Synonym(s): Merkel corpuscle

Merkel cell, Merkel disk

found in the basal layer of the epidermis; believed to act as slow-acting tactile endorgans.

Merkel cell tumor
see neuroendocrine cell tumor.
References in periodicals archive ?
Differential expression of thyroid transcription factor 1 in small cell lung carcinoma and Merkel cell tumor.
A similar result of discordant LT and VP1 positive Merkel cell tumor samples has been reported (8).
MCPyV was reported in 2008 and was identified in Merkel cell tumors, a rare form of skin cancer (8).
Genta Incorporated (Nasdaq: GNTA) announced today the publication of a paper that reports a new treatment strategy for an aggressive form of cancer, known as Merkel cell tumor.
Metastatic Merkel cell tumor to the prostate and bladder.
Vulvar Merkel cell tumor with glandular and squamous differentiation.
F-18 accumulation in an octreotide negative Merkel cell tumor.
Merkel cell tumors typically present as painless, nonulcerated areas of skin thickening or plaque.
Establishment and characterization of two Merkel cell tumor cultures.
Archival cases of Merkel cell tumors were identified from the records of the Tumor Registry at the Reading Hospital and Medical Center.
Merkel cell tumors behave so aggressively in transplant patients that it's probably a poor idea to offer transplantation to anyone with a history of this form of cancer, he added.