Merbentyl


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dicyclomine (dicycloverine (UK))

Bentyl, Bentylol (CA), Diclophen (CA), Formulex (CA), Lomine (CA), Merbentyl (UK), Protylol (CA)

Pharmacologic class: Anticholinergic

Therapeutic class: Antispasmodic

Pregnancy risk category B

Action

Thought to exert direct effect on GI smooth muscle by inhibiting acetylcholine at receptor sites, thereby reducing GI tract motility and tone

Availability

Capsules: 10 mg

Solution for injection: 10 mg/ml

Syrup: 10 mg/5 ml

Tablets: 20 mg

Indications and dosages

Irritable bowel syndrome in patients unresponsive to usual interventions

Adults: 20 mg P.O. or I.M. q.i.d.; may increase up to 160 mg/day

Contraindications

• Hypersensitivity to drug
• GI or genitourinary tract obstruction
• Severe ulcerative colitis
• Reflux esophagitis
• Unstable cardiovascular status
• Glaucoma
• Myasthenia gravis

Merbentyl

A brand name for DICYCLOMINE HYDROCHLORIDE (dicycloverine).