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mephenesin

   Also found in: Wikipedia 0.01 sec.
mephenesin (mefen´isin),
n an antispasmodic drug, 3 ortho-toloxyl, 2 propanediol. Used for the preparation of apprehensive patients for dental and periodontal procedures because of its ability to produce muscular relaxation and euphoria. Usual dosage for an adult is 1 gm in either tablet or elixir form, 20 minutes before the dental procedure.

mephenesin
a centrally acting muscle relaxant. Once used in association with pentobarbital for anesthesia, but no longer used because of its many side-effects, including venous thrombosis and hemolysis.


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Despite aggressive treatment including breath-holding to interrupt the respiratory rhythm, continuous positive airway pressure, and medication with metoclopramine, prochlorperazine, chlorpromazine, haloperidol, mephenesin, diphenylhydantoin, baclofen, and phenobarbital, the hiccups persisted for 7 days.
Experientia 26: 283-284 Meyer HJ, Kretzschmar R (1966) Kawa pyrones: a new group of components in central muscle relaxing agents of the mephenesin type.
But a post-race drug test returned positive for the little-known drug mephenesin.
 
 
 
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