A prospective randomized trial of single-agent versus combinacion chemotherapy in meningeal carcinomatosis
(MC) is rare and occurs in 1-18% of patients with solid tumours, most commonly carcinomas of the breast and lung or melanomas.
is the tumoral invasion of the leptomeninges.
Due to recurrent characteristics of hypertensive encephalopathy, chronic bacterial and fungal infections of the central nervous system, a current cerebrovascular accident and central nervous system vasculitis, and meningeal carcinomatosis
There is no difference in the appearance comparing to meningeal carcinomatosis
, lymphoma, leukemia, tuberculosis and fungus meningitis [5, 6].
from small cell carcinoma of the lung.
There was one case of cerebral tonsillar herniation caused by cerebral edema because of meningeal carcinomatosis
The etiology is diverse and includes infectious, granulomatous and inflammatory disorders, collagen vascular disorders, carcinoma, lymphoma, meningioma en plaque, sarcoidosis, haemodialysis, mucopolysaccharidosis, intrathecal drug administration, and meningeal carcinomatosis
Advanced MRI could help to differentiate meningeal carcinomatosis
with mass effect from cerebral metastasis in prostate cancer.
This is also known as meningeal carcinomatosis
, and can be caused by primary neuro ectodermal tumours such as neuroblastoma, tumours of the haemopoietic system such as lymphoma, or solid tumours metastasizing to the leptomeninges (e.
Nakagawa H, Murasawa A, Kubo S et al: Diagnosis and treatment of patients with meningeal carcinomatosis
suggested that when the sulci or cisterns show areas of hyperintensity on unenhanced FLAIR images in patients with cancer, meningeal carcinomatosis
is strongly suspected and contrast-enhanced FLAIR images should be obtained (4).