GPER

(redirected from Membrane oestrogen receptor)

GPER

A gene on chromosome 7p22.3 that encodes a G protein-coupled receptor that binds oestrogen and is widely distributed in neural, breast cancer, placental, heart, ovarian, prostate, hepatic, vascular epithelial and lymphoid tissue. It plays a role in rapid nongenomic signalling events seen after oestrogen stimulation of cells and tissues.
References in periodicals archive ?
Resistance to tamoxifen-induced apoptosis is associated with direct interaction between Her2/neu and cell membrane oestrogen receptor in breast cancer.
Membrane oestrogen receptors on rat pituitary tumour cells: immunoidentification and responses to oestradiol and xenoestrogens.
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