progressive bacterial synergistic gangrene

(redirected from Meleney's gangrene)

Me·le·ney ul·cer

undermining ulcer of the skin and subcutaneous tissues caused by a synergistic infection by microaerophilic nonhemolytic streptococci and aerobic hemolytic staphylococci; may also include various other aerobic and anaerobic organisms.

progressive bacterial synergistic gangrene

A mixed bacterial (microaerophilic streptococci, Staphylococcus aureus or Enterobacteriaceae) infection that appears at surgical margins, most commonly after abdominal and thoracic procedures, beginning days to weeks after surgery. While it is severely painful, there is remarkably little systemic toxicity.


Frank L., U.S. surgeon, 1889-1963.
Meleney gangrene - Synonym(s): Meleney ulcer
Meleney infection
Meleney ulcer - undermining ulcer of the skin and subcutaneous tissues, usually following an operation. Synonym(s): Meleney gangrene; progressive bacterial synergistic gangrene
References in periodicals archive ?
3) Unfortunately, the literature regarding skin and soft tissue NIs is confusing, contains errors and misinterpreted data, and includes the use of nonstandard or outdated terms in historical articles such as hospital gangrene, Meleney's gangrene, suppurativa fasciitis, necrotizing erysipelas, and acute dermal gangrene.
But this infection's appearance is so distinctive and the consequences of missing it so grave that Meleney's gangrene should be on every ob.