Melacine

Melacine

An allogeneic melanoma tumour cell lysate combined with the adjuvant Detox, which was used as an anti-tumour vaccine and had some (minimal) benefit for advanced and metastatic melanoma, and in melanoma patients who expressed HLA-I A2 and/or HLA-C3.
References in periodicals archive ?
Results of clinical trials with an allogenic melanoma tumor cell lysate vaccine: Melacine.
For example, M-Vax, OncoVax and Melacine, the first three therapeutic vaccines to reach the international market, have all sold poorly as each has been launched in only a small number of nations.
The manufacturer of the Melacine melanoma vaccine is planning to finalize plans for a second pivotal trial of the vaccine in people with stage II disease.
The manufacturer of the Melacine melanoma vaccine plans to finalize plans for a second, pivotal trial of the vaccine in people with intermediate-thickness stage II disease, now that a Food and Drug Administration expert panel has agreed to the proposed study design.
Mitchell MS, Von Eschen KB: Phase III trial of Melacine melanoma theraccine versus combination chemotherapy in the treatment of stage IV melanoma (Abstract).
On February 15, Corixa and Schering Canada, a wholly owned subsidiary of Schering-Plough Corporation, announced the immediate availability in Canada of Corixa's Melacine vaccine, a therapeutic vaccine for treatment of Stage IV melanoma.
Corixa Corporation (Nasdaq:CRXA), a research and development-based biotechnology company, has released additional data from its Phase III, randomized trial to evaluate Corixa's therapeutic vaccine Melacine, for the treatment of Stage II melanoma.
Melacine is currently in the Food and Drug Administration approval process.
ABX MA1, Alfanative , ALLOVECTIN-7, AP 12009, Avastin, BAY 504798, Canvaxin, Carboplatin, Carmustine, Ceplene Maxamine, Cisplatin, CP 4055, Dacarbazine, Dexosome, Didemnin B, Ecromeximab, Elea Vaccine, EMD 273063, Enhanzyn, F 50040, Genasense, GMK, GV 1001, GVAX, Iboctadekin, ILX 651, INGN 241, INO 1001, Intron A, Kahalalide F, Karenitecin, KOS 953, Lenalidomide, Lomeguatrib, MDX-010, Melacine, Melphalan, MJV 101, M-VAX, NOVOVAC-M1, NY-ESO-1 ISCOMS, Oncophage, OncoVax, OncoVEXGM-CSF, Paclitaxel, PD 0325901, Peginterferon alfa-2b, Pivanex, Proleukin , ProMune, QS-21, SB 249553, SB 715992, Sorafenib, Talabostat, Tamoxifen, Temozolomide, Temozolomide, Uvidem, Vinblastine/Vinorelbine, Virulizin, Vitaxin, Zadaxin
DCVax), Gastrimmune, GMK, LymphoCide, Melacine, M-Vax, MyVax, Oncophage, OncoVAX, Osidem, Ovarex, Provenge, Theratope, TriGem, TroVax and many more.
Corixa's cell therapy Melacine is based on the "cell vaccine" concept and consists of lysed (broken) cells from two human melanoma cell lines combined with Detox adjuvant.
Other cancer vaccine strategies that are on the way are Actimmune, Allovectin-7, Avicine, BEC2, Canvaxin, CeaVac, Gastrimmune, GMK, LymphoCide, Melacine, Ovarex, Oncophage, Osidem and.