meglumine antimonate

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meglumine antimonate

A drug used in treating leishmaniasis.
See also: meglumine
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According to local protocols, patients were treated with 20 mg/kg of intramuscular meglumine antimoniate or with 18-38 mg/ kg of intravenous liposomal amphotericin B; at publication time, the patients were still being followed.
The first choice treatment of CL is pentavalent antimony compounds including meglumine antimoniate (MA) and sodium stibogluconate (SSG), which are widely prescribed despite their toxicity, high cost, difficulty in administration and emergence of resistant parasites (6-8).
GTM or meglumine antimoniate is a synthetic anti-leishmanial drug based on pentavalent antimonial (Sbv) that have been clinically recommended as first line drug to treat the infections by L.
There are two common therapies containing antimony (known as pentavalent antimonials), meglumine antimoniate (Glucantime) and sodium stibogluconate (Pentostam).
Toxicity and efficacy of the antileishmanial drug meglumine antimoniate in the owl monkey (Aotus trivirgatus).
Pharmacokinetics of antimony during treatment of visceral leishmaniasis with sodium stibogluconate or meglumine antimoniate.
The patients who presented from 1995 up to 2000 were treated with meglumine antimoniate (MA) (Glucantim; Rhone-Poulenc, France) whereas those who presented thereafter were treated with L-AmB (AmBisome; Gilead, USA).
Comparison of Intralesionally Injected Zinc Sulfate with Meglumine Antimoniate in the Treatment of Acute Cutaneous Leishmaniasis.
In one treatment study in Lima, Peru, 40 patients with cutaneous Leishmania infections were random ized to a standard, injected regimen of meglumine antimoniate (Glucantime) alone, or to the same regimen plus topical treatment with imiquimod (Aldara).
Finally, the most common treatment was intramuscular meglumine antimoniate (Glucantime) (24.
Intralesional or systemic antiparasitic pentavalent antimonials such as sodium stibogluconate or meglumine antimoniate are the gold standard for the treatment of these diseases.
Given the patient's older age and the fact that lesion was isolated, intralesional treatment with meglumine antimoniate was initiated.