mechanism of action

(redirected from Mechanisms of action)
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mechanism of action

(1) The manner in which a therapeutic agent acts, which includes blocking of receptors, enzymes, stimulating hormone production, etc. 
(2) The physiologic or biochemical processes within the body that are affected by a drug’s action, producing a given response.

mechanism of action

The means by which a drug exerts its effects on cells or tissues. It may have specific binding sites, receptor activation, enzymatic activity, or solubility.
See also: mechanism
References in periodicals archive ?
The major goal of this PEA is to support research focused on the mechanisms of action by which the mammalian innate immune system responds to the food and waterborne protozoa from the NIAID Category B Priority Pathogens list.
Drug candidates arising from these projects could shorten the treatment time for patients with TB and, because of their novel mechanisms of action, treat patients who are resistant to conventional therapies.
Mechanisms of action for antimicrobial agents: general principles and mechanisms for selected classes of antibiotics.
A review of the mechanisms of action and resistance of antimicrobial agents.
Many toxicogenomics studies are providing expression data for toxicants that have known mechanisms of action, with the eventual goal of inferring mechanisms of action for novel compounds.
The goals of single molecule research are to observe the dynamic behavior of individual molecules, to explore heterogeneity among molecules, and to determine mechanisms of action.
CRx-102 and CRx-139 are oral synergistic combination drug candidates with novel mechanisms of action targeting multiple biological pathways simultaneously.
Lunastatin[TM] was found to have two powerful mechanisms of action.
Specifically, the FDA has cleared KCI to market and label the unique mechanisms of action of the V.
This new clearance is significant because it further substantiates the unique mechanisms of action of V.
The significant glucose-lowering efficacy seen in this study suggests complementary mechanisms of action of sitagliptin and metformin resulting in an additive effect when both agents are given together," said Barry J.
In addition, the Company reported that it has made significant progress in defining the mechanisms of action of its Hormonal Signaling Technology Platform.