mechanism of action


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mechanism of action

(1) The manner in which a therapeutic agent acts, which includes blocking of receptors, enzymes, stimulating hormone production, etc. 
(2) The physiologic or biochemical processes within the body that are affected by a drug’s action, producing a given response.

mechanism of action

The means by which a drug exerts its effects on cells or tissues. It may have specific binding sites, receptor activation, enzymatic activity, or solubility.
See also: mechanism
References in periodicals archive ?
The combination of a potentially new mechanism of action and an attractive safety profile makes this compound potentially useful either alone or in combination with existing alternatives.
CRx-191 works through a novel mechanism of action in which nortriptyline amplifies mometasone's anti-inflammatory activities without expectation of enhancing steroid side effects such as skin atrophy.
37 Coridon Pty Ltd 38 Human papillomavirus (HPV) Associated Cancer - Therapeutics Assessment 39 Assessment by Monotherapy Products 39 Assessment by Target 40 Assessment by Mechanism of Action 42 Assessment by Route of Administration 44 Assessment by Molecule Type 46 Drug Profiles 49 V-503 - Drug Profile 49 Product Description 49 Mechanism of Action 49 R&D Progress 49 rigosertib sodium - Drug Profile 51 Product Description 51 Mechanism of Action 51 R&D Progress 51
In preclinical studies MIV-410 has been shown to have a novel mechanism of action against HIV, enabling it to retain activity against several HIV mutants with resistance to thymidine analogs (TAM mutants) and nucleoside analogs (NAM mutants).
22 Perrigo Company plc 23 Encephalomyelitis - Therapeutics Assessment 24 Assessment by Monotherapy Products 24 Assessment by Target 25 Assessment by Mechanism of Action 28 Assessment by Route of Administration 31 Assessment by Molecule Type 33 Drug Profiles 34
22 MGB Biopharma Limited 23 Infectitious Diarrhea - Therapeutics Assessment 24 Assessment by Monotherapy Products 24 Assessment by Target 25 Assessment by Mechanism of Action 28 Assessment by Route of Administration 31 Assessment by Molecule Type 33 Drug Profiles 35
This report provides comprehensive information on the therapeutic development for Recurrent Malignant Glioma, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
Drug Profiles 14 Monoclonal Antibodies for Seasonal Influenza 14 Product Description 14 Mechanism of Action 14 R&D Progress 14 Bispecific Monoclonal Antibodies for Seasonal and Pandemic Influenza 15 Product Description 15 Mechanism of Action 15 R&D Progress 15 Monoclonal Antibodies for Gastrointestinal Diseases 16 Product Description 16 Mechanism of Action 16 R&D Progress 16
This is a more sophisticated mechanism of action than that of prescription statin drugs that only suppress the enzymatic activity of HMG-CoA reductase after it has already been produced.
NASDAQ: POTP) announced today that talabostat's Phase 2 non-small cell lung cancer (NSCLC) program and dual mechanism of action was presented on Saturday, September 16, 2006 at the 14th International Conference on Gene Therapy of Cancer in Dallas, Texas.
The mechanism of action of DPP-4 inhibitors is distinct from that of any currently available class of glucose-lowering agents.
Talabostat is a new targeted anti-cancer agent believed to work through a novel dual mechanism of action that inhibits select dipeptidyl peptidases (DPPs).