mechanism of action


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mechanism of action

(1) The manner in which a therapeutic agent acts, which includes blocking of receptors, enzymes, stimulating hormone production, etc. 
(2) The physiologic or biochemical processes within the body that are affected by a drug’s action, producing a given response.

mechanism of action

The means by which a drug exerts its effects on cells or tissues. It may have specific binding sites, receptor activation, enzymatic activity, or solubility.
See also: mechanism
References in periodicals archive ?
The combination of a potentially new mechanism of action and an attractive safety profile makes this compound potentially useful either alone or in combination with existing alternatives.
The results obtained in the CARLA provided evidence for a molecular mechanism of action of the test compounds via hER that is distinct from that of [E.
Talabostat's mechanism of action is extremely interesting and with the positive results we saw in the Phase 2 non-small cell lung cancer trial, we thought this was a nice opportunity to introduce talabostat to a wider audience," explained Dr.
The mechanism of action of DPP-4 inhibitors is distinct from that of any currently available class of glucose-lowering agents.
USPRwire, Tue Aug 22 2017] This report provides comprehensive information on the current therapeutic developmental pipeline of TechnoPhage SAs, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
Talabostat is a new targeted anti-cancer agent believed to work through a novel dual mechanism of action that inhibits select dipeptidyl peptidases (DPPs).
USPRwire, Mon Aug 21 2017] This report provides comprehensive information on the current therapeutic developmental pipeline of Toleranzia ABs, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
Through years of research with these compounds -- metabolic conversions or synthetic analogs of adrenal steroid hormones -- Hollis-Eden has made significant discoveries relating to their metabolism, mechanism of action and pharmacologic profile.
Panacos has confirmed the mechanism of action of these compounds in additional functional assays.
USPRwire, Tue Jun 27 2017] This report provides comprehensive information on the current therapeutic developmental pipeline of Inventiva SASs, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.