MCP-1


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MCP-1

MCP-1

Monocyte chemoattractant protein-1. An older term for a CC cytokine which is critical for development of atherosclerotic lesions, found in endothelial cells, macrophages and in vascular smooth muscle cells of patients undergoing coronary artery bypass procedures. The officially preferred term is now chemokine (C-C motif) ligand 2.
References in periodicals archive ?
MCP-1 (Monocyte Chemoattractant Protein 1, also named CCL2) belongs to the CC chemokines family and is induced in response to various inflammatory stimuli.
5), the MCP-1 levels were elevated only in patients with PDA.
Two chemokine panels (Biosource and Upstate) were chosen to compare with ELISAS for the analysis of MCP-1 and eotaxin.
The aim of this study was to investigate possible correlations between polymorphisms in the genes encoding for MCP-1, RANTES, SDF-1, and CCR5 and breast cancer clinical phenotypes, specifically the ability of genetic analysis to identify a subgroup of breast cancer patients with a disease that appears more aggressive or prone to metastasize.
Cross-sectional study design was applied to compare the difference in serum level of cytokines, IL-1[beta], TNF-[alpha] and MCP-1, between schizophrenia patients and HCs.
In this study, we investigated the extent to which adipocytes contribute to overall increases in oxLDL-mediated MCP-1 levels in 3T3-L1 adipocytes.
Increased expression of both MCP-1 and its receptor CCR2 may mediate increased pain signaling through direct excitation of DRG neurons, as well as through attracting macrophages to the DRG," the researchers said.
Keywords: Myocardial infarction Tanshinone IIA Salvia miltiorrhiza Inflammatory responses Cardiac fibroblast MCP-1 TGF-[[beta].
In particular, in accordance with some embodiments, there are provided fully human monoclonal antibodies directed to the antigen MCP-1.
The 8-week study looked at blood markers for vascular inflammation, including TNF-a, MCP-1, retinol binding protein-4 (RBP-4), cholesterol and triglycerides in obese Zucker diabetic rats.