MCP-1


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MCP-1

MCP-1

Monocyte chemoattractant protein-1. An older term for a CC cytokine which is critical for development of atherosclerotic lesions, found in endothelial cells, macrophages and in vascular smooth muscle cells of patients undergoing coronary artery bypass procedures. The officially preferred term is now chemokine (C-C motif) ligand 2.
References in periodicals archive ?
Increased expression of both MCP-1 and its receptor CCR2 may mediate increased pain signaling through direct excitation of DRG neurons, as well as through attracting macrophages to the DRG," the researchers said.
Therefore, the present study determined the effect of Tan IIA on the expression of MCP-1 and TGF-[[beta].
The sections were then incubated with Polyclonal antibody against MCP-1 (Santa Cruz, USA) and Polyclonal antibody against nuclear transcription factor-kappa B (NF-[kappa]B) p65 (Boster, China) at a dilution of 1:50 for 120 min at room temperature.
TF production has been reported to be regulated by numerous stimuli, including MCP-1 (20), CRP (16), and hemodynamic forces (21).
After extraction of total RNA and proteins, we measured the TF and MCP-1 mRNA and MCP-1 protein.
7 ng/L for IL-8, MCP-1, EGF, and VEGF (variant 165), respectively.
Because we could not obtain all results for IL-8, MCP-1, EGF, and VEGF (17.
MCP-1 (Monocyte Chemoattractant Protein 1, also named CCL2) belongs to the CC chemokines family and is induced in response to various inflammatory stimuli.
5), the MCP-1 levels were elevated only in patients with PDA.
In the patients who had IPMN, high levels of MCP-1 also correlated with older age.
Two chemokine panels (Biosource and Upstate) were chosen to compare with ELISAS for the analysis of MCP-1 and eotaxin.
The aim of this study was to investigate possible correlations between polymorphisms in the genes encoding for MCP-1, RANTES, SDF-1, and CCR5 and breast cancer clinical phenotypes, specifically the ability of genetic analysis to identify a subgroup of breast cancer patients with a disease that appears more aggressive or prone to metastasize.