MMP1

(redirected from Matrix metalloproteinase-1)

MMP1

A gene on chromosome 11q22.3 that encodes matrix metalloproteinase 1, which cleaves collagens I, II and III in the helical domain, as well as collagens VII and X. MMP1 interacts and cleaves HIV’s secreted Tat protein, reducing neuronal Tat-mediated neurotoxicity.
References in periodicals archive ?
Matrix metalloproteinase-1 production observed after solar-simulated radiation exposure is assumed by dermal fibroblasts but involves a paracrine activation through epidermal keratinocytes.
This effectively prevented infrared-A radiation-induced matrix metalloproteinase-1 messenger RNA expression in human skin.
Impact of plasma tissue inhibitor of matrix metalloproteinase-1 on long-term survival in patients with colorectal cancer.
Matrix metalloproteinase-1 is associated with poor prognosis in colorectal cancer.
The contribution of the genetic variations of the matrix metalloproteinase-1 gene to the genetic susceptibility of gastric cancer.
Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonary emphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke.
Further study the effect of this compound on MMP-2 posttranslational modification which regulated by membrane-type matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 [31] are interested to be explored.
Matrix metalloproteinase-1 and -8 in gingival crevicular fluid during orthodontic tooth movement: a pilot study during 1 month of follow-up after fixed appliance activation.
DEP evokes the secretion of matrix metalloproteinase-1 (MMP-1) from human bronchial epithelia, which is important because MMP-1 plays a role in tissue remodeling during respiratory disease processes.
Berberine induced downregulation of matrix metalloproteinase-1, -2 and -9 in human gastric cancer calls (SNU-5) in vitro.
Angiotensin II increases human monocyte matrix metalloproteinase-1 through the AT2 receptor and prostaglandin E2: implications for atherosclerotic plaque rupture.

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