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maternal age effect |
Also found in: Wikipedia | 0.02 sec. |
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maternal age effect The adverse impact that ↑ age has on obstetric events: ↑ complication rate, ↑ fetal defects–possibly due to an unknown effect of aging on the uterus and eggs; ↑ frequency of non-disjunctional
events in Down syndrome and other aneuploidies, as well as Prader-Willi syndrome, in which there is uniparental disomy of chromosome 15. See Elderly primigravida. Cf Paternal age.
Maternal age & chromosome defects
Age Trisomy 21 Others
<20 1/1900 1/526
25 1/1200 1/476
30 1/885 1/384
35 1/365 1/178
40 1/109 1/63
45 1/32 1/18
49 1/12 1/7
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