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Mast cell |
Also found in: Wikipedia, Hutchinson | 0.03 sec. |
Mast cell A cell found in connective tissue that releases substances such as heparin and histamine in response to injury or inflammation of bodily tissues. Mentioned in: H-2 Blockers mast cell, n a connective tissue cell whose specific physiologic function remains unknown; capable of elaborating basophilic, metachromatic, cytoplasmic granules that contain histamine. mast cell a cell that may be derived from an undifferentiated precursor, which may be of monocytic origin, in the perivascular connective tissue. It elaborates granules that contain histamine, heparin and, in the rat and mouse, serotonin. It plays an important role in acute hypersensitivity (type I) reactions such as atopy and anaphylaxis. mast cell leukemia see mast cell leukemia. mast cell tumor a benign, local aggregation of mast cells forming a nodular tumor that occurs in the skin of most species, but most commonly in dogs. The release of histamine or other vasoactive substances may be associated with gastroduodenal ulceration. These tumors may become malignant. See also mastocytosis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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