Marsh classification

Marsh classification

A system used to grade the histologic severity of coeliac disease based on assessment of duodenal biopsies, which show blunting of villi and the intraepithelial lymphocyte-to-enterocyte ratio.
References in periodicals archive ?
Biopsy samples with grade 2 or more on Modified Marsh Classification were considered as consistent with celiac disease.
Modified Marsh Classification was used to grade the histopathology of biopsy samples.
Investigation of celiac disease according to Marsh classification in childhood.
All the cases were classified according to the Marsh classification.
Since the fifties, the diagnosis of coeliac disease has depended on duodenal biopsy findings that include different degrees of villous atrophy along with crypt hyperplasia and intraepithelial lymphocytosis, which are graded by the Marsh classification (Marsh I-IIIC) (3,4).
Recently, Ensari has proposed an updated version of the time-honored Marsh classification, which is much simpler, and user-friendly from a pathologist\'s point of view.
Marsh classification will be discussed in detail in association with other classification schemes in the following sections.
Marsh classification is composed of 4 consecutive states of mucosal damage (types 1-4) as follows.
Morphology was categorized according to the modified Marsh classification (1, 22).
Table 2 also shows the histological characteristics of small-bowel biopsies according to the modified Marsh classification.
patients and 3b in 4 patients according to modified Marsh classification (Table-I).