marker gene


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to marker gene: Marker chromosome

marker gene

marker gene

A variant allele used to label a biological structure or process throughout an experiment. Marker genes are located in a constant genomic position in a particular organism.

marker gene

a gene whose location and characteristics are well-known and which is used to investigate other genes; for example, to determine the location of any gene relative to the marker gene.
References in periodicals archive ?
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences.
Some plant species, most notably grasses, are more amenable to transformation by particle bombardment, which generally involves cotransformation of two separate plasmids or DNA molecules, one for the gene of interest and one for the marker gene.
We have used transgenic techniques to produce animals bearing a gene for the collagen [alpha]1(IV) chain containing a single point mutation at the proposed CBS in combination with marker genes rol-6 (su1006) and Green fluorescent Protein (GFP).
Further, European Food Safety Authority has also reaffirmed that aadA gene encoding resistance against spectinomycin/streptomycin pose no threat to humans or to the environment, thus a potential selectable marker gene for plant transformation (EFSA, 2009).
Yamanaka and his colleagues now describe online and in an upcoming Nature how they also inserted a novel marker gene that singled out the completely reprogrammed stem cells.
For Agrobacterium tumefaciens-mediated transformation, strain LBA4404 harboring a T-DNA containing the translational fusion gene cry1Ab-1B driven by the maize ubiquitin constitutive promoter along with its first intron and untranslated exon (Christensen and Quail, 1996) and bar (coding for phosphinothricin acetyltransferase) as the selectable marker gene, under the control of the 70S promoter (double enhanced constitutive 35S promoter from Cauliflower mosaic virus), (Fig.
The Commission says several member states then raised objections to the import of the maize "in terms of molecular characterisation, allergenicity, toxicity, inadequate monitoring plan, accidental spillage, presence of antibiotic resistance marker gene and detection of the product".
The transfer of marker genes to target cells depends on the function of the envelope protein; therefore, the titer of neutralizing antibodies against the envelope can be measured by a reduction in marker gene transfer.
The approval of this marker gene was a regulatory blunder committed in the United States and elsewhere, as it is clear that kanamycin is still widely in clinical use, and the marker gene confers resistance to new generation aminoglycosides as well (6).
PPL said each of the 5 piglets, born in the United States, has a foreign marker gene in its DNA structure, a major step toward the production of genetically engineered pig organs for use in human transplantation.
The controversial technology requires the use of an antibiotic-resistant marker gene, which confers resistance to certain antibiotics in the people who eat GE foods.
Amflora potato and three hybrid maize (MON863xMON810, MON863xNK603, MON863xMON810xNK60") - these products contain an antibiotic marker gene.