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Marek's disease
(redirected from Marek's disease virus)

   Also found in: Acronyms, Wikipedia 0.01 sec.
Marek's disease
a transmissible disease of chickens caused by an alphaherpesvirus that carries some retrovirus oncogenes; characterized by a tumorous, mononuclear infiltration of peripheral nerves, causing limb paralysis. Infiltration of other organs and tissues is common, especially of the iris, causing blindness, and of the ovaries. Vaccination is highly effective and without it serious outbreaks with heavy losses can occur. Called also neural lymphomatosis, neurolymphomatosis gallinarum.


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Several novel criteria have been tested to assist in the differential diagnosis of tumors induced by Marek's disease virus (MDV) from those induced by avian leukosis virus (ALV) and reticuloendotheliosis virus (REV).
Coussens conducted research on the molecular biology of Marek's disease virus, an oncogenic alpha-herpesvirus.
 
 
 
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