Marek's disease


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Marek's disease

a transmissible disease of chickens caused by an alphaherpesvirus that carries some retrovirus oncogenes; characterized by a tumorous, mononuclear infiltration of peripheral nerves, causing limb paralysis. Infiltration of other organs and tissues is common, especially of the iris, causing blindness, and of the ovaries. Vaccination is highly effective and without it serious outbreaks with heavy losses can occur. Called also neural lymphomatosis, neurolymphomatosis gallinarum.
References in periodicals archive ?
Now, the modified PCR allows any laboratory to extract virus DNA from preserved tissues to detect Marek's disease and reticuloendotheliosis.
B-haplotype influence on Marek's disease, Rous sarcoma, and lymphoid leukosis virus-induced tumors in chickens.
Holding the line against tumor-causing Marek's disease has required the nonstop diligence of poultry researchers.
Hilleman pioneered the development of numerous vaccines including those for hepatitis A, both plasma-derived and recombinant hepatitis B, measles, mumps, rubella, MMR, pneumococcus, meningococcus and Marek's Disease.
Marek's disease (MD) virus (MDV) is an [alpha]-herpesvirus that causes MD, a lymphoproliferative disease in chickens.
A questionnaire was widely distributed in 2011 to estimate the global prevalence of Marek's disease (MD) and gain a better understanding of current control strategies and future concerns.
Embrex is best known for its Inovoject(R) system, now used to vaccinate more than 80 percent of the poultry raised in North America against Marek's disease.
Before the map, Cheng had found what he thinks are three genes that confer resistance to Marek's disease, his chief interest.
In both cases, test results were negative for Marek's disease virus, avian leukosis virus, and reticuloendotheliosis virus.
In an advance that could usher in new vaccines for protecting poultry, Agricultural Research Service (ARS) scientists have sequenced the genetic code of the chicken herpesvirus that causes Marek's disease.
Comparison of blood and feather pulp (FP) samples for the diagnosis of Marek's disease (MD) and for monitoring Marek's diseases vaccination in chickens (serotypes 2 and 3 vaccines) by real time-PCR was evaluated.