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maraviroc

   Also found in: Wikipedia 0.02 sec.
maraviroc,
an antiretroviral.
indication This drug is used to treat CCR5-tropic HIV in combination with other antiretroviral agents.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects of this drug include dizziness, depression, disturbances in consciousness, peripheral neuropathy, paresthesia, dysesthesia, fever, gingival hyperplasia, diarrhea, constipation, dyspepsia, rash, urticaria, pruritus, folliculitis, joint pain, leg pain, muscle cramps, cough, upper respiratory infection, sinusitis, bronchitis, pneumonia, and herpes virus. Life-threatening side effects include MI, cardiac ischemia, orthostatic hypotension, viral meningitis, pseudomembranous colitis, hepatotoxicity, bronchospasm, and respiratory obstruction.


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Subgroup analyses of maraviroc in previously treated R5 HIV-1 infection.
Many of the panel members disclosed financial ties to multiple manufacturers of antiretroviral drugs, including the manufacturers of maraviroc (Pfizer Inc.
The updated recommendations also give a boost for using recently-approved drugs, including raltegravir, maraviroc and etravirine, in combination with older treatments to keep down viral levels and boost CD4 counts.
 
 
 
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