Mansonella perstans

Man·son·el·la per·'stans

the "persistent filaria," a species widely prevalent in tropic Africa and northern South America where it infects human peritoneal and other body cavities, but is nonpathogenic or only mildly so; characteristic subperiodic microfilariae occur in peripheral blood. It is transmitted in Africa by the biting midges Culicoides austeni and C. grahami.

Mansonella perstans

a long, thread-like worm usually found in Africa. It commonly infects wild and domestic animals and occasionally invades the bloodstream of humans, causing a rash, muscle and joint pains, various neurological disorders, and nodules in the subcutaneous tissues. The larvae are also found in the cerebrospinal fluid of affected patients.

Mansonella perstans

A filarial nematode which causes serosal filariasis in humans.

Epidemiology
Subsaharan Africa, Central and South America, Caribbean.

Vector
Haematophagous midges (genus Culicoides).

Clinical findings
Generally banal, with moderate fever, articular pain, headache, pruritis, rash, pulmonary symptoms, lymphadenopathy and hepatomegaly.
 
Management
Ivermectin is effective against microfilariae, but not against adult worms.

Mansonella perstans

A species of filaria that is transmitted to humans by Culicoides insects (midges). It was formerly known at Acanthocheilonema perstans.

Symptoms

Angioedema, urticaria, high blood eosinophil levels, and other findings.

See also: Mansonella
References in periodicals archive ?
Molecular identification of Wolbachia from the filarial nematode Mansonella perstans.
Five species of filarial parasites have been reported in Nigeria, namely Wuchereria bancrofti, Onchocerca volvulus, Loa loa, Mansonella perstans, and Mansonella streptocerca (6-9).
Mansonella perstans microfilaraemia among the Bori community in the Niger Delta area of Nigeria.
Most (tissue-dwelling) filariases (apart from a few blood-dwelling species such as Mansonella perstans which cause little harm), including onchocerciasis, loiasis and bancroftian filariasis, cause distinct pathologies including characteristic and extensive skin lesions (in long-standing disease).
loa and Mansonella perstans are endemic to the study region, which is in the equatorial rainforest, and malaria is hyperendemic in the region (1,4).
Mansonella perstans is transmitted by tiny biting midges of the genus Culicoides.
The filarial nematode Mansonella perstans is endemic to countries in central and western Africa; its distribution overlaps that of other filarial nematodes W.
bancrofti from microfilariae of Mansonella perstans and Loa-loa if present.
2001-2002 (2) progressive epileptic encephalopathy; weak associations with measles, sorghum, and baboon brain consumption; stronger associations with testing for onchocerciasis and Mansonella perstans nematodes Tanzania, Winkler et al.
Of these, 258 were Onchocerca volvulus infections, 124 were Mansonella perstans infections, 29 were Loa loa infections, and 7 were M.
Filarial species detected by direct methods were Mansonella perstans (n = 13), Loa loa (n = 4), and Onchocerca volvulus (n = 1).