methaqualone

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methaqualone

 [meth″ah-qua´lōn]
a nonbarbiturate compound formerly used as a sedative and hypnotic; now found only as a drug of abuse. See drug abuse.

methaqualone

(mĕth′ə-kwā′lōn′)
n.
A potentially habit-forming drug, C16H14N2O, formerly used as a sedative and hypnotic.

methaqualone

An addictive Schedule-II hypnotic-sedative quinazolone with barbiturate-like effects which, when it was legal, was used to reduce anxiety and tension. It was a popular drug of abuse, and it was linked to physical or psychologic dependence.

Clinical findings
Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anaemia.
 
Route
Oral, injected, sniffed, smoked.
 
Management of overdose
Haemoperfusion.

Toxic range
> 8 µg/mL, serum; > 300 µg/L, urine.
 
T1/2
20–60 hours.
 
Specimen
Serum, random urine.
 
Method
GC.

methaqualone

Quaalude, 'ludes' Substance abuse An addictive Schedule II hypnotic-sedative quinazolone with barbiturate-like effects; methaqualone was a popular drug of abuse and linked to physical or psychologic dependence Clinical Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anemia Route Oral, injected, sniffed, smoked Used for Anxiety, tension Management Hemoperfusion. See Controlled drug substance.

methaqualone

a nonbarbiturate hypnotic similar to barbiturates in its effects.
References in periodicals archive ?
Armed with the dangerous knowledge, Dudani started manufacturing the psychotropic substance in the form of Mandrax tablets weighing 1.
The data suggest an association between use of amphetamine or Mandrax and longer DUP.
and an Emirati senior government official from Umm Al Quwain, with smuggling huge quantities of methacolone and some acids that they used to manufacture more than six million Mandrax pills.
Oficialmente nunca se aclaro el uso que se planeaba dar al ecstasy y al mandrax.
Most of those who reported trying other illicit drugs first had tried cannabis or the cannabis/ Mandrax (methaqualone) combination first.
South Africa, while suffering from the trafficking and use of dagga and mandrax, was shielded from much of the growth of narcotics trafficking that has taken place in the rest of the world in the last two decades.
He turned to drink to cope with his grief, although he says his alcohol dependence goes back to his days as a player when he used to use Mandrax - which is now banned - to help him sleep.
In the process of going regional, they have expanded to more criminal activities, such as new trades in illicit drugs (including heroin, mandrax, and cocaine), arms, light weapons, and other merchandise of war.
TABLE 3 Selected illicit psychoactive substance use as well as the use of inhalants in Youth KAP studies in Southern Africa (in percentages and rounded to whole numbers) South Africa Tanzania Zambia Old Stone Kanyama Bela-Bela Pretoria Town & Chinika Variable n=109 n=193 n=299 n=398 Cannabis use Lifetime use 10 11 14 14 Use last 12 months 6 6 10 7 Use last 30 days 4 3 9 4 Inhalants use Lifetime use 3 6 2 47 Use last 12 months -- 3 2 34 Use last 30 days -- -- -- 19 Mandrax use Lifetime use 1 1 3 -- Use last 12 months 1 -- 2 -- Use last 30 days 1 -- -- -- Heroin use Lifetime use -- 1 9 * Use last 12 months -- 1 4 * Use last 30 days -- -- 3 * * Less than 0.
It is small credit to Zopaclone, which I now take (after Sodium Amytal, Mogadon, Mandrax and Halcion were, each in turn, considered too dangerous) that, come 2.
I stood at the back of a loo in a Stockholm hotel suite and watched him coax Keith Moon into pouring his supply of Mandrax sleeping pills down the pan.