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malignant neuroleptic syndrome

   Also found in: Wikipedia 0.02 sec.
malignant neuroleptic syndrome
A complex that affects < 1% of Pts exposed to neuroleptics–phenothiazine, butyrophenones Clinical Onset 1-3 days after beginning antidepressant therapy, which causes hyperthermia, autonomic instability, muscle rigidity, myoglobinuria


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Parkinsonian-like * Perphenazine movements * Methotrimeprazine Malignant neuroleptic syndrome Atypical (second minor sedation, hypotension, sexual xerostomia, generation) dysfunction, Metabolic syndrome: dysphagia, Antipsychotics increased incidence Type 2 diabetes, stomatitis, * Clozapine obesity, hyperlipidemia, heart dysgeusia * Olanzapine disease.
The differential diagnosis of the serotonin syndrome in turn includes malignant neuroleptic syndrome (MNS), MAOI overdose, tyramine reaction, strychnine ingestion, and the use of cocaine, amphetamines or other sympathomimetic drugs.
 
 
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