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Malignant |
Also found in: Wikipedia, Hutchinson | 0.02 sec. |
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malignant /ma·lig·nant/ (-nant) 1. tending to become worse and end in death. 2. having the properties of anaplasia, invasiveness, and metastasis; said of tumors.
Malignant The term literally means growing worse and resisting treatment. It is used as a synonym for cancerous and connotes a harmful condition that generally is life-threatening. Mentioned in: Abdominal Ultrasound, Breast Cancer, Colon Cancer, Gallium Scan of the Body, Hairy Cell Leukemia, Laryngeal Cancer, Lymph Node Biopsy, Multiple Myeloma, Radical Neck Dissection, Rectal Cancer, Skin Biopsy, Wilms' Tumor malignant (m adj type of cancerous growth with a tendency to metastasize and grow unchecked. See also metastasis. malignant (m adj 1. resistant to treatment. 2. able to metastasize and kill the host. 3. describing a cancer. malignant hypertension, n the most lethal form of high blood pressure. It is a fulminating condition, characterized by severely elevated blood pressure that commonly damages the intima of small vessels, the brain, retina, heart, and kidneys. It affects more persons with racial diversity and may be caused by a variety of factors such as stress, genetic predisposition, obesity, the use of tobacco, the use of oral contraceptives, high intake of sodium chloride, a sedentary lifestyle, and aging. malignant hyperthermia, n an autosomal dominant trait characterized by often fatal hyperthermia with rigidity of muscles occurring in affected people exposed to certain anesthetic agents, particularly halothane and succinylcholine. malignant tending to become progressively worse and to result in death; having the properties of anaplasia, invasiveness and metastasis; said of tumors. malignant aphtha see contagious ecthyma. malignant carbuncle a form of anthrax in humans. malignant catarrhal fever (MCF) an acute highly infectious, fatal herpesvirus disease of cattle, farmed deer and occasionally pigs characterized by an erosive stomatitis and gastroenteritis, erosions on the mucosa of the upper respiratory tract, keratoconjunctivitis, encephalitis, and lymphadenopathy. There are at least two viruses involved. A wildebeest-associated form of the disease is caused by alcephaline herpesvirus 1. It occurs in most African countries in cattle which co-mingle with clinically normal wildebeest and hartebeest. It is epizootic and seasonal. It can also occur in zoological gardens in other countries. Sheep-associated MCF is caused by a poorly characterized virus, presumably ovine herpesvirus 2 (OvHV-2). Cases mostly occur when cattle have had contact with lambing ewes and usually start 1-2 months later. Goats can also act as a source of OvHV-2 infection for cattle. Cases without apparent or recent exposure to sheep do occur but are uncommon. Called also bovine malignant catarrh. malignant edema an acute infection of wounds by Clostridium septicum, C. chauvoei, C. perfringens, C. sordellii or C. novyi. The inflammation causes severe swelling and discoloration of skin and exposed tissues. There may be local subcutaneous emphysema and a frothy exudate, depending on the identity of the invading organism. There is a high fever and a profound toxemia; death follows within a few hours if treatment is not provided. Special occurrences are when a large number of animals are affected at one time. These include involvement of the vulva in recently lambed ewes, of shearing or docking wounds, and of the umbilicus or eyes of recently born lambs. malignant fibrous histiocytoma a rare aggressive tumor of dogs and cats; composed of densely packed fibroblasts and histiocytes. malignant head catarrh malignant histiocytosis see malignant histiocytosis. malignant hyperthermia see malignant hyperthermia, porcine stress syndrome. malignant lymphoma see lymphosarcoma. malignant pustule see malignant carbuncle (above). malignant theileriasis theileriasis caused by Theileria hirci. |
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