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Mace
(redirected from Major Adverse Cardiovascular Events)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
Mace or MACE (ms)
An alternate trademark for Chemical Mace, an aerosol used to immobilize an attacker temporarily.

mace
[mās]
the oil-containing, red, fibrous wrapping of the nutmeg kernel. Dried and ground, it is used as an aromatic spice and flavoring. Compare Mace.

Mace,
trademark for a chemical lacrimator. The name is an abbreviation formed by letters in methylchloroform-2-chloroacetophenone, which is dispersed from a pressurized container to immobilize an attacker.

MACE
An acronym for objective measures of acute and/or adverse cardiovascular events (e.g., acute myocardial infarction, ischaemic stroke, coronary arterial occlusion, death) which are used to assess the effects of various interventions (e.g., rotablation, angioplasty, stenting) or therapeutics (e.g., antiarrhythmics, statins, ACE inhibitors) on outcomes, in the context of a clinical trial.

Mace [mās]
trademark for an aerosol mixture of CS, a common tear gas.


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Specifically, the letter stated that "before your application can be approved, you must conduct a randomized, double-blind, placebo-controlled trial of sufficient size and duration to demonstrate that the risk of major adverse cardiovascular events in overweight and obese subjects treated with naltrexone/bupropion does not adversely affect the drug's benefit-risk profile.
The article is entitled South Asian Ethnicity as a Risk Factor for Major Adverse Cardiovascular Events After Renal Transplantation.
The decision was based on results from the Sibutramine Cardiovascular Outcomes (SCOUT) trial, a postmarketing study conducted at the request of European health authorities, which found that the risk of major adverse cardiovascular events (a composite of nonfatal heart attack, nonfatal stroke, resuscitation after cardiac arrest, and cardiovascular death) was 16% higher among sibutramine-treated patients compared with those on placebo.
 
 
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