mafenide


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mafenide

 [maf´en-īd]
a compound used in the form of the acetate and hydrochloride salts for topical treatment of infections.

mafenide

/maf·en·ide/ (maf´in-īd) an antibacterial, used topically as the monoacetate salt in superficial infections.

mafenide

a sulfonamide that is not inhibited by the presence of pus and necrotic tissue; used mostly for local application to infected wounds. Called also homosulfanilamide, sulfamylon.
References in periodicals archive ?
In vitro toxicity and activity of Dakin's solution, mafenide acetate, and amphotericin B on filamentous fungi and human cells.
3% (OTC) Mupirocin Cream USP, 2% Glenmark Rosiglitazone Maleate Tablets, 2 mg (base), Teva 4 mg (base), 8 mg (base) FEBRUARY 2013 Doxorubicin Hydrochloride Liposome Sun Pharma Injection LISP, 2 mg/ml, packaged in 20 mg/10 ml and 50 mg/25 ml single-use vials Mafenide Acetate, USP for 5% Topical Par Pharmaceutical Solution, 50 g sterile powder per packet Fludeoxyglucose F18 Injection USP, Houston Cyclotron 20-500 mci/ml @ EOS Partners Buprenorphine HCI and Naloxone HCI Amneal Dihydrate Sublingual Tablets, 2 mg (base)/0.
Topical 5 percent mafenide acetate solution (5% Sulfamylon Solution) was found to be bactericidal against many nosocomial Acinetobacter isolates, and wound-care protocols suggest its use in place of normal saline for washing wounds [21].
Off-label drug use in WOC nursing: Issues related to use of mafenide acetate to treat infected chronic wounds.
Limited success has also been seen with non-antibiotic remedies such as chlorohexidine, nitrofurazone, PVP-I, mafenide and mupirocin.
18-24) Povidone iodine has a bacteriostatic therapeutic life of 4 hours following a single topical application, mafenide acetate 12 hours and silver sulphadiazine (AgSD) 1% up to 36 hours.
Mafenide acetate is a drug with good penetration that can prevent infection, and Dr.
The wound was cleansed, hemostasis obtained, and the wound was dressed with gauze dressings soaked in 5% solution of mafenide acetate (Sulfamyalon).