macrolide

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macrolide

 [mak´ro-līd]
1. a chemical compound characterized by a large lactone ring containing multiple keto and hydroxyl groups.
2. any of a group of antibacterial antibiotics containing such a ring linked to one or more sugars.

mac·ro·lide

(mak'rō-līd),
A natural lactone with a large ring; usually consisting of 14-20 atoms; macrolides include a class of antibiotics discovered in streptomycetes, for example, erythromycin; macrolides also inhibit protein biosynthesis.

macrolide

/mac·ro·lide/ (mak´ro-līd)
1. a compound characterized by a large lactone ring with multiple keto and hydroxyl groups.
2. any of a group of antibiotics containing this ring linked to one or more sugars, produced by certain species of Streptomyces.

macrolide

(măk′rō-līd)
n.
A class of antibiotics that are produced by certain actinomycetes of the genus Streptomyces, are characterized by a large lactone ring linked to one or more sugars, and act by inhibiting protein synthesis.

macrolide

A natural lactone with a large (14–20) carbon ring structure that inhibits protein synthesis; e.g., erythromycin.

mac·ro·lide

(mak'rō-līd)
A natural lactone, with a large ring, usually of 14-20 atoms; several antibiotics, including erythromycin, are macrolides. They inhibit protein biosynthesis.

macrolide

One of a range of antibiotics with a wide spectrum of action that can be used as an alternative to the penicillins to treat respiratory infections including LEGIONNAIRES' DISEASE. The group includes erythromycin, azithromycin and clarithromycin.

macrolide

as in antibiotic; any antibiotic with molecules having many-membered lactone rings, e.g. erythromycin, spiramycin, tylosin.
References in periodicals archive ?
One is to continue to use macrolide antibiotics and waiting for the resolution of clinical symptoms, because fatal outcome of M.
From the results it showed that newer macrolide antibiotics also found to have anti-inflammatory action which are in supportive with study conducted by Angela Ianaro et al in 2000.
For example, the macrolide antibiotic azithromycin can be quite toxic to the inner ear in patients who are undergoing treatment for human immunodeficiency virus (HIV) infection.
CREATOGEN diagnostics develops and markets a new class of diagnostic kits which facilitate the rapid identification of bacteria with the simultaneous detection of their sensitivity towards macrolide antibiotics.
WASHINGTON -- Oral azithromycin produced "moderate to marked" improvement in acne rosacea patients without causing the gastrointestinal side effects typical of other macrolide antibiotics, Dr.
Macrolide antibiotics have proven to be valuable alternatives to pencillins and cephalosporins for the treatment of a number of infections.
Key Topics Covered: - China Antibiotics Market In Globalization Process, 2009 - China Antibiotics Foreign Trade, 2007-2008 - China Antibiotics Market, 2008 - China Antibiotics Market after 2010 - China Anti-Infective Drug Market - China Antibiotics Retail Market - Children Oral Antibiotics Market - Cephalosporins Antibiotics Market - Penicillin Antibiotics Market - Carbapenem Antibiotics Market - Macrolide Antibiotics Market - Quinolones Antibiotics Market - Beta-lactams Antibiotics Market - Polypeptide Antibiotics Market - Market Competition - List of Charts Companies Mentioned: - Yangtze River Pharmaceutical Group - Shanghai Roche Pharmaceuticals Co.
18) Mycoplasma pneumoniae, which typically produces a mild "walking" pneumonia, has demonstrated increasing resistance to macrolide antibiotics (likely associated with the widespread use of azithromycin), with wide geographic variability, ranging from 7% in Seattle to 50% in New Jersey.
Macrolide antibiotics are so named because they contain a many membered lactone ring to which one or more deoxy sugars are attached.
Potential role of macrolide antibiotics in the management of cystic fibrosis lung disease.
SAN FRANCISCO -- Drug resistance was a common cause of treatment failure in 26 patients with community-acquired pneumonia who developed bacteremia while being treated with macrolide antibiotics, Dr.
The system was evaluated following an outbreak of pertussis in a small institutional setting in a rural county by comparing the county's CUSUM signals for prescriptions for macrolide antibiotics with the onset of the outbreak.