MYO15

MYO15

Notation for the gene for myosin 15.

MYO15A

A gene on chromosome 19p13.1 that encodes a protein belonging to the myosin family of actin-based molecular motor heavy chain proteins, which binds calmodulin, which serves as a light chain. The MYOB/calmodulin complex displays processive movement on actin filaments toward the minus-end.

Molecular pathology
MYOB polymorphisms are associated with coeliac disease and ulcerative colitis.