MYH6

MYH6

A gene on chromosome 14q12 that encodes a heavy chain of myosin and is thus involved in cytokinesis, cell shape and specialised functions—e.g., secretion and capping.
 
Molecular pathology
MYH6 mutation causes familial hypertrophic cardiomyopathy and atrial septal defect 3.
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References in periodicals archive ?
Did the authors exclude mutations in nDNA-located genes which have been shown to cause dCMP, such as MYH7 , MYBPC3 , LMNA , TNNI3 , TNNT2 , ACTC1 , TPM1 , SCN5A , MYL2 , MYH6 , MYL3 , PLEKHM2 , HAND1 , RBM20 , FBXO32 , DES , YBPC3 , MYPN , and PRKAG2 ?
miR-208a and miR-208b are encoded by introns in the MYH6 (myosin, heavy chain 6, cardiac muscle, alpha) and MYH7 genes, respectively.
Source:RefSeq mRNA;Acc:NM_213740] ENSSSCG00000030 999 MYH6 myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576] ENSSSCG00000002 029 MYH7 Sus scrofa myosin, heavy chain 7, cardiac muscle, beta (MYH7), mRNA.
A rare variant in MYH6 is associated with high risk of sick sinus syndrome.