MUSTIC

MUSTIC

Abbreviation for:
Multisite Stimulation in Cardiomyopathy
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Cardiac resynchronizasation may reduce all-cause mortality: meta-analysis of preliminary COMPANION data with CONTAK-CD, InSync ICD, MIRACLE, and MUSTIC.
A number of trials that have shown this, including the MIRACLE (Multicenter InSync Randomized Clinical Evaluation) trial, which appeared in the NEJM, and the MUSTIC (Multi-site Stimulation in Cardiomyopathy) trial, published in the NEJM the year before.
Medtronic has supported seven major heart failure studies that have contributed to guidelines, including SCD-HeFT, REVERSE, MIRACLE, MIRACLE ICD, MIRACLE ICD II, MUSTIC, and CARE HF studies.
ELA also sponsored the first prospective randomized trial - the MUSTIC study - which assessed the efficacy of CRT in heart failure patients.
The results reinforce evidence from earlier Medtronic-supported trials, such as MUSTIC, MIRACLE and MIRACLE ICD, that have shown dramatic benefits of CRT for many heart failure patients, including improved exercise capacity, quality of life and clinical symptoms.
ELA also sponsored the first prospective randomized trial -- the MUSTIC study -- which assessed the efficacy of CRT in heart failure patients.
Other major clinical trials supported by Medtronic such as MUSTIC, MIRACLE and MIRACLE ICD have shown dramatic benefits of CRT for many heart failure patients, including improved exercise capacity, quality of life and clinical symptoms.
CRT pioneer Angelo Auricchio (Magdeburg, Germany) explained that three randomized controlled trials (PATH-HF, MUSTIC and MIRACLE) have already shown that CRT improves HF functional status (NYHA class), and increases exercise capacity and quality of life.
In the past decade, Medtronic has enrolled nearly 9,000 patients in more than 20 heart failure clinical studies, including MUSTIC, MIRACLE, MIRACLE ICD, SCD-HeFT, CARE-HF, and BLOCK HF.
CRT pioneer Angelo Auricchio (Magdeburg, Germany) explained that three randomised controlled trials (PATH-HF, MUSTIC and MIRACLE) have already shown that CRT improves HF functional status (NYHA class), and increases exercise capacity and quality of life.