MMP15

(redirected from MT-MMP 2)

MMP15

A gene on chromosome 16q13 that encodes matrix metalloproteinase 15, an endopeptidase that degrades components of the extracellular matrix and may activate progelatinase A. Unlike other matrix metalloproteinases, which are secreted as inactive proproteins and activated when cleaved by extracellular proteinases, MMP15 is a transmembrane protein that is activated from its precursor by furin endopeptidase cleavage.