MAP3K10

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MAP3K10

An oncogene on chromosome 19q13.2 that encodes a MAPK kinase kinase belonging to a protein kinase signal transduction cascade. MAP3K10 can be phoshorylated, and is thus activated by JNK kinases. It
preferentially activates MAPK8/JNK and the JNK signalling pathway, but also acts on MKK4/SEK1. It is reported to be involved in nerve growth factor (NGF)-induced neuronal apoptosis. It is expressed in brain and skeletal muscle.

Each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of three protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which in turn activates a specific MAPK.
References in periodicals archive ?
Chellie Pingree (D-Maine) introduced legislation that would make it easier for veterans who suffered MST during their service to get the disability benefits and medical coverage they deserve.
Borduin readily admits that MST is more expensive initially because of the extent of the therapy that takes place in the home, schools, and community.
At the time MST organizers came into Pernambuco, the sugar industry was in a deep depression.
MST is pragmatic and goal-oriented in its approach to treating youths and their families.
MST has now delivered more than half of the initial order to a number of opencast mining sites in Spain.
Possible clues to identifying MST in men include substance abuse (often severe), problems with sexual intimacy, difficulties with male relationships, marital relationship problems, problems with authority, fear of being labeled homosexual or sexually impotent, history of child sexual abuse or exposure to abuse, anger and aggression, and a history of violence.
MST (NuVisions[TM]) will install a full lineup of television programming along with High Speed Internet Access and Digital Voice.
The MST has been a core constituency that has expressed its dissatisfaction at the moderation of Lula's governing Partido dos Trabalhadores (PT).
To make the collectives more effective, Brazil doesn't have to rid itself of agribusiness, as MST hardliners argue.
At least 40 percent of agricultural land -- the MST says 60 percent -- lies fallow or, at best, is used only for cattle grazing.
392), should have read "FROM ARVIND VENIGALLA, MBA, MST, AND BRENDA ZENT, CPA, MST, WASHINGTON, DC.
In 1998, CMS MST ranked as the 36th-largest power marketer for commercial and industrial customers, based on volume traded.