9-Sep

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9-Sep

A gene on chromosome 17q25 that encodes septin 9, a member of the septin family of nucleotide-binding proteins, which are required for cytokinesis, organisation of submembranous structures, neuronal polarity and vesicle trafficking. SEPT9 is a candidate for ovarian tumour suppressor gene.

Molecular pathology
SEPT9 mutations cause hereditary neuralgic amyotrophy (neuritis with brachial predilection). A translocation between SEPT9 and MLL on chromosome 11 results in acute myelomonocytic leukaemia.
References in periodicals archive ?
Indeed, on a total of 85 strains, only (6) strains (MSC1, MSC19, MSF1, MSF22, MSH17, MSH21) have survived in the presence of AM10 and (2) strains (MSC1, MSF22) in the presence of CN10.
The evaluation of the intrinsic resistance to the antibiotics reveal that all strains of four geographical groups have presented a remarkable sensitivity in the presence of AM and CN except some strains (MSC1, MSC19, MSF1, MSF22, MSH17, MSH21) and (MSC1, MSF22) that have made proof of resistance to these antibiotics, respectively.
Two strains of the fungi MSF1 and MSF2 were identified under the microscope on the basis of morphological characteristics (Domsch et al.
Balfour Beatty, which is on a number of public sector infrastructure frameworks including the Constructing West Midlands and Construction Framework South West, also held a position on the previous framework for the Midlands Highways Alliance MSF1, through which it was awarded 24 out of 60 projects and carried out over Au110 million of work.