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Monoamine oxidase inhibitor
(redirected from MOA Inhibitor)

    Also found in: Wikipedia 0.01 sec.
monoamine oxidase inhibitor
n. Abbr. MAOI
Any of a class of antidepressant and hypotensive drugs that block the action of monoamine oxidase in the brain, thereby allowing the accumulation of monoamines such as norepinephrine.
Monoamine oxidase inhibitor (MAOI)
An older class of antidepressants.
Mentioned in: Antidepressant Drugs, SSRI
monoamine oxidase inhibitor Pharmacology An inhibitor of monoamine oxidase, which inactivates monoamines Examples Brofaromine, isocarboxazid, moclobemide, pargyline, phenelzine, selegeline, tranylcypromine; herbal MAOIs–eg, hypericum, yohimbe Adverse interactions Cheeses and wines with high concentrations of tyramine–metabolized by monoamine oxidase, may trigger epinephrine and norepinephrine release, hypertensive crises, stroke; MAOIs should not be combined with SRIs


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