DYRK1A

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DYRK1A

A gene on chromosome 21q22.13 that encodes a member of the dual-specificity tyrosine-phosphorylation-regulated kinase (DYRK) family, which catalyses its autophosphorylation on serine/threonine and tyrosine residues. DYRK1A may play a key role in a signalling pathway that regulates cell proliferation and may be involved in brain development. 

Molecular pathology
DYRK1A is a candidate gene for learning defects associated with Down syndrome.
References in periodicals archive ?
But it's the reason for MNB that I've not always been entirely honest about.
In the Air Force contract MNB provided the hardware only; for other customers it can provide customized software as well.
MNB was set up after the Russian Revolution as a foreign trade bank.
The court noted that MNB fit the exception illustrated in this example.
With insufficient reserves to cover the debt, MNB entered administration, effectively allowing the company to trade only with the permission of the courts - and was forced to slash its workforce from 70 to 28.
But under the guidance of local businessman Michael Quinn, MNB fought back to pay its creditors and has now doubled its workforce from 25 to 50.
Regardless of the nation, the G2 operations sections from each MNB needed to feel free to talk directly to each other without the need to go through KFOR headquarters.
To have rescued MNB and put it back on a sound financial footing within three months is excellent news for the business and its creditors.
The bank said, 'The MNB considers it important that the reduction of the bank tax should be accompanied with a significant rise in lending.
6 million in September, but it would have sold for more had MNB not filed its lawsuit that accused Ed Harvey of transferring his assets to Bonnie in order to avoid paying a $1.