MIRACLE ICD

MIRACLE ICD

Abbreviation for:
Multicentre InSync™ Randomized Clinical Evaluation Implantable Cardioverter Defibrillator
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Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial.
Medtronic has supported seven major heart failure studies that have contributed to guidelines, including SCD-HeFT, REVERSE, MIRACLE, MIRACLE ICD, MIRACLE ICD II, MUSTIC, and CARE HF studies.
MIRACLE / MIRACLE ICD (Multicenter InSync / ICD Randomized Clinical Evaluation) studies: initiated in 1998 and 1999, respectively, evaluated NYHA Class III, IV patients for six months and demonstrated significant improvements in quality of life and cardiac function.
medical director of the Kaufman Center for Heart Failure at The Cleveland Clinic Foundation, co- principal investigator of the study and chairman of the MIRACLE ICD steering committee.
The results reinforce evidence from earlier Medtronic-supported trials, such as MUSTIC, MIRACLE and MIRACLE ICD, that have shown dramatic benefits of CRT for many heart failure patients, including improved exercise capacity, quality of life and clinical symptoms.
Physicians will evaluate the performance of the Medtronic Attain SD cardiac vein lead model 4189, as part of the ongoing MIRACLE ICD trial (Multicenter InSync Randomized Clinical Evaluation in ICD patients).
Other major clinical trials supported by Medtronic such as MUSTIC, MIRACLE and MIRACLE ICD have shown dramatic benefits of CRT for many heart failure patients, including improved exercise capacity, quality of life and clinical symptoms.
clinical trial called MIRACLE ICD, physicians will evaluate the performance of this new combined therapy product.
The study, called MIRACLE ICD II, evaluated the use of cardiac resynchronization therapy defibrillators in patients with mild symptoms, and showed that these patients demonstrated significant improvement in both cardiac structure and function, as well as improvements in their overall clinical response.
In the past decade, Medtronic has enrolled nearly 9,000 patients in more than 20 heart failure clinical studies, including MUSTIC, MIRACLE, MIRACLE ICD, SCD-HeFT, CARE-HF, and BLOCK HF.
Since 1997, we have supported 20 heart failure clinical studies, including MIRACLE, MIRACLE ICD, SCD-HeFT and CARE-HF.
Evidence supporting the benefits of cardiac resynchronization therapy (CRT) for heart failure patients continues to mount, with results of the MIRACLE ICD clinical study published in the May 28 issue of the Journal of the American Medical Association (JAMA).