MGUS


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Related to MGUS: multiple myeloma

MGUS

MGUS

Monoclonal gammopathy of unknown significance, see there.

MGUS

Abbreviation for monoclonal gammopathy of unknown significance.

Monoclonal gammopathy of undetermined significance (MGUS)

Common condition in which M-protein is present, but there are no tumors or other symptoms of disease.
Mentioned in: Multiple Myeloma

Patient discussion about MGUS

Q. Does anyone know anything about MGUS?

A. MGUS is a condition that affects a type of white blood cell known as a plasma cell. Plasma cells are a type of white blood cell that produce special proteins, known as antibodies or immunoglobulins. These antibodies circulate in the blood, ready to attack any viruses and bacteria that may be present in the body.
When an abnormally large amount of one particular antibody is produced, this is called monoclonal gammopathy. All the antibodies are identical.

More discussions about MGUS
References in periodicals archive ?
2] Nonstandard abbreviations: MGUS, monoclonal gammopathies of undetermined significance; SPE, serum protein electrophoresis; CZE, capillary zone electrophoresis; IFE, Immunofixation electrophoresis; FLCR, free light chain ratio; MS, mass spectrometry; TOF, time of flight; ESI, electrospray ionization.
Disease entity M-protein MGUS <30 g/L Smoldering Myeloma >30 g/L in serum Or >1 g/24hour in the urine Symptomatic Myeloma Any value Solitary Plasmacytoma All of the following: Biopsy proven solitary lesion No clonal plasma cells in the bone marrow An otherwise normal skeletal survey and MRI of the spine and pelvis No end organ damage Disease entity Clonal PCs in BM MGUS <10% Smoldering Myeloma >10% Symptomatic Myeloma >10% <10% if other criteria are met Solitary Plasmacytoma Disease entity End-organ Others damage (CRAB *) MGUS No No other B-cell lymphoproliferative disorder Smoldering Myeloma No Symptomatic Myeloma Yes Solitary Plasmacytoma * CRAB: Hyper-Calcemia serum calcium >2.
Most MGUs do have written underwriting guidelines but those guidelines are just for underwriting, not for pricing.
The blood of the participants, aged 30-94, was assessed for MGUS prevalence.
Mobile device use is pervasive among carriers and MGUs, but laptops have lost appeal in the field.
Mobile device use has grown among carriers and MGUs, with respondents preferring to use tablets over smartphones for uses other than phone calls: 62 percent of respondents prefer to use tablets for tasks other than phone calls, compared to 21 percent for smartphones.
I don't think you can adequately manage MGU relationships without a good team approach; there's just too much complexity, too many moving parts," Dresner said.
It was during an annual blood check that the myeloma, which in a very small number of cases can develop from MGUS, was first detected.
provider of insurance software solutions for global insurance carriers, MGAs and MGUs, today announced that the global insurance and reinsurance company, XL Group plc (XL) (NYSE: XL), has selected the FirstBest Underwriting Management System (UMS) as the foundation of their Global Underwriting Platform.
On the other hand, 16% of IFE-only MGUS were not found on subsequent testing and had no known intervention to explain the loss of the M-protein (20).
The firms Lloyds syndicate, ANV 1861 proceeds to offer the majority share of the capacity under the MGUs Lloyds binding authority.
2 yrs) Prasad et al, (10) 1998 Lymphoplasmacytic NA lymphoma Sun et al, (11) 2003 MALT lymphoma NED (9 months) Papla et al, (4) 2004 Multiple myeloma Dead (postoperative) lonescu et None (rheumatoid NA al, (14) 2005 arthritis) Fairweather MALT lymphoma NED (4 months) et al, (12) 2006 Lee et al, (15) 2009 None (treated NA tuberculosis) Todd et al, (16) 2010 MGUS Stable nodule (2 years) Ko et al, (17) 2012 MALT lymphoma NA Abbreviations: LP-PCD, lymphoproliferative/plasma cell disorder; MALT, mucosa-associated lymphoid tissue; MGUS, monoclonal gammopathy of undetermined significance; NA, not available; NED, no evidence of disease.