METAVIR scoring system

METAVIR scoring system

A system used to assess inflammation and fibrosis by histopathological evaluation of a liver biopsy of patients with hepatitis C. The grade indicates the activity or degree of inflammation, and the stage represents the amount of fibrosis or scarring.

Activity grade
• A0—No activity.
• A1—Mild activity.
• A2—Moderate activity.
• A3—Severe activity.
Fibrosis stage
• F0—No fibrosis.
• F1—Portal fibrosis without septa.
• F2—Portal fibrosis with few septa.
• F3—Numerous septa without cirrhosis.
• F4—Cirrhosis.
References in periodicals archive ?
Fibro-SURE (LabCorp), for example, uses a peripheral venous blood sample and combines the patient's age, gender, and 6 biochemical markers to generate a range of scores that correspond to the fibrosis component of the well-known METAVIR scoring system and correlate with results of liver biopsies.
The patients were divided into two groups according to the stage of hepatic fibrosis using the METAVIR scoring system (F0-F2 vs.
The Fibroscan (Echosense, Paris) was used for the measurement of liver stiffness and METAVIR scoring system was used for calculating liver stiffness measurement (LSM) values ranging from 3.
Liver biopsies were analyzed for the fibrosis stage in each center by the local pathologist, using the METAVIR scoring system.
The Metavir scoring system is a histological assessment of the degree of inflammatory activity and the stage of fibrosis.
Re-examination of the liver biopsy classified the specimen as F1A2 according to the METAVIR scoring system.
The integrated database included published prospective studies of chronic hepatitis C patients with concomitant FT measurement and liver biopsy, who had liver biopsies scored using the METAVIR scoring system (5), had FT assessed on fresh serum using the recommended preanalytical and analytical procedures, and had individual data sent by the principal investigator.
Studies were included if fibrosis had been evaluated using the METAVIR scoring system, the diagnostic value was expressed using the AUC and the prevalence of different fibrosis stages was given.
A pathologist who was unaware of the biochemical markers evaluated the fibrosis stage and necrosis grade according to the METAVIR scoring system (5).
Hepatic histological evaluation was graded and staged according to the Metavir scoring system.
who was unaware of the results for the biochemical markers, evaluated the stage of fibrosis and grade of activity according to the METAVIR scoring system (20, 21).
00, corresponding to stages FO-F4 and grades A0-A3 of the well-established METAVIR scoring system.