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MERLIN
(redirected from MERLIN-TIMI 36)

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MERLIN
(1) Merlin. A cytoskeleton scaffolding protein [OMIM 607379] which links actin filaments to cell membrane glycoproteins. It is primarily located in nervous tissue, but is also present in foetal tissues at adherens junctions.
(2) MERLIN-TIMI 36. Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndromes. A trial that evaluated the efficacy and safety of long-term ranolazine in patients with non-ST-elevation acute coronary syndromes who were receiving standard therapy
Conclusion The only parameter to reach statistical significance was recurrent ischaemia, which was lower in ranolazine—14%—than in placebo patients—16%; p = 0.03. There were no difference in total mortality with ranolazine vs. placebo; p = 0.91
(3) MERLIN. Middlesbrough Early Revascularization to Limit Infarction
merlin
falcocolumbarius.
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Also added to the label is a statement that cites the significantly lower rate of arrhythmias in patients with coronary heart disease who were treated with ranolazine in the MERLIN-TIMI 36 trial, compared with those on placebo, CV Therapeutics Inc.
Ranolazine label has new claims, fewer restrictions by Mechcatie, Elizabeth / Internal Medicine News
As we have seen in the MERLIN-TIMI 36 trial and in clinical practice, patients with ischemia and angina can be at increased risk for arrhythmias and also often have diabetes.
FDA Approves Ranexa(R) for First Line Anti Anginal Use and Adds New ... by PR Newswire
002), a signal of ischemia, in these MERLIN-TIMI 36 angina patients.
CV Therapeutics' Anti-Ischemic Therapy Ranexa(R) Significantly ... by PR Newswire
 
 
 
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