MEN (redirected from MEN type 1-I)

MEN multiple endocrine neoplasia.

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MEN,

abbreviation for multiple endocrine neoplasia.

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MEN

Multiple endocrine neoplasia, Multiple endocrine adenomatosis A group of AD, often overlapping diseases characterized by hyperplasia or neoplasia of > one endocrine gland, many of the APUD system, see there

MEN–multiple endocrine neoplasia

MEN type 1–I A complex characterized by pituitary adenoma or hyperplasia, adrenal adenoma or hyperplasia, parathyroid adenoma or hyperplasia, acromegaly, pancreatic islet cell tumors–insulinoma, carcinoid, Zollinger-Ellison syndrome, WDHA syndrome, ↑ gastrin secretion, peptic ulcer, Note: Nonhereditary factors may influence the expression of MEN I as the condition may be unequally expressed in identical twins; the defective gene is located on chromosome 11q13 Lab Invest 1995; 72:494

MEN type 2a–I/IIa A complex characterized by medullary carcinoma of the thyroid–bilateral and present in nearly 100% of cases producing calcitonin, histaminase, prostaglandins, ACTH, potentially causing Cushing syndrome, pheochromocytoma and parathyroid adenoma or hyperplasia Diagnosis Conventional diagnostic modalities–eg radiologic imaging, histopathology, and laboratory values–↑ plasma calcitonin, ↑ urinary catecholamines, and catabolites, for MEN-2A identifies relevant tumors, but not carriers Molecular pathology The MEN-2A gene mutation identified by linkage analysis in the RET proto-oncogene, which maps to chromosome 10q11.2, specifically at exon 10 or 11, is highly specific–no false positives and highly sensitive–no false negatives, allowing early diagnosis of MEN-2A.  See RET gene Prognosis Excellent

MEN type 2b–III/IIb Mucosal neuroma syndrome A complex characterized by bilateral medullary carcinoma of the thyroid–producing calcitonin, histaminase, prostaglandins, ACTH and potentially, Cushing syndrome, pheochromocytoma, parathyroid adenoma or hyperplasia, mucosal–gut neurofibromas, associated with thickened lips, submucosal oral nodules, intestinal ganglioneurofibromatosis, infantile intestinal dysfunction and cranial nerve hyperplasia and connective tissue disease–Marfanoid habitus, scoliosis, kyphosis, pectus excavatum Prognosis 20% mortality  

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Patient discussion about MEN type 1-I.

Q. can serious mood fluctuations be caused in young men by anything else but bipolar? My brother is suffering (well we are suffering it as well...) some serious moods. It's not like he's just upset or anything like that. He has never acted this way. It has been really hard to communicate with him lately and I'm worried. no way to get him checked, he's unwilling. We dont have bipolar in the family, well, yet. any suggestions?

A. The picture you describe may result from many causes. Does he use drugs or anything like that? Does he have hard time these days at work/school/home etc? It may cause different moods. Schizophrenia may present in way similar to what you describe. In my opinion, consulting a professional (e.g. a psychiatrist, because it's not really feasible to diagnose it based on your 5-lines description) may be wise, It's not necessarily bipolar, if that's what you ask.

Take care

Q. Do they make any specal kind of a supporter for older men that have very low hanging scrotums?

A. look for jock straps,or whitey,tighties,

Q. Does a women wear men's deodorant can get breast cancer? I love partying. I used to go out with my boyfriend on Saturdays to dance clubs. I am crazy about the fragrance of my boyfriend’s deodorant. One day I asked him to lend his deo to me for just one party. He said that men’s deo can cause breast cancer in ladies. I am afraid of using it. But I could not overcome my feelings. I like to try it out once, only once. Is it true that women that wear men's deodorant can get breast cancer? (I love the fragrance of Old spice!)

A. naaaa! that's just an urban myth. there isn't any difference between women's or men's deodorant. neither of them should cause breast cancer... but they both contain aluminum which is generally not good for you.

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