MEN 2B


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MEN 2B

An inherited neoplasia syndrome characterised by medullary thyroid carcinoma, phaeochromocytoma, mucocutaneous ganglioneuromas and a marfinoid habitus.

Molecular pathology
A single amino acid change is present in RET oncogene (met918thr) on chromosome 10.
References in periodicals archive ?
All of the patients had inherited MTC (MEN 2A, MEN 2B, or FMTC) and had known genomic RET mutations previously analyzed by sequence analysis (by S.