malondialdehyde-modified LDL

(redirected from MDA-LDL)
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malondialdehyde-modified LDL

A low-density lipoprotein, which is chemically modified in vivo, thought to reflect naturally occurring oxidation of LDL and serve as a surrogate marker for significant atherosclerosis; it is thus useful as a biochemical marker of coronary artery disease.
References in periodicals archive ?
We compared MDA-LDL concentrations in each distribution range of LDL size between control subjects and patients with DM and with hypertriglyceridemia (Fig.
For DM patients, the concentrations of MDA-LDL and apo B for patients in the LDL size ranges <25.
When MDA-LDL concentrations in 20 randomly selected subjects were compared with the corresponding TBARS concentrations in LDL isolated by ultracentrifugation, we found no correlation between variables (r = 0.
When the MDA-LDL concentration was evaluated as an index of LDL oxidation (19), it was higher in subjects with DM or hypertriglyceridemia than in control subjects.
We assessed the relationship between LDL size and TG concentration by measuring MDA-LDL concentrations in corresponding subgroups (Fig.
5 nm and with increased TGs showed more significantly increased concentrations of MDA-LDL.
When we examined the relationship between LDL size and the concentration of MDA-LDL in control subjects and patients with DM or hypertriglyceridemia, we found that LDL particle diameters and MDA-LDL concentrations were inversely related in all groups (Fig.