MC5R

MC5R

A gene on chromosome 18p11.2 that encodes a receptor for alpha, beta and gamma melanocyte stimulating hormone (MSH), the activity of which is mediated by G protein-activated adenylate cyclase. MC5R is thought to mediate the immunomodulatory properties of melanocortins and may play a role in sebum production.
References in periodicals archive ?
Essa classe de receptores tem seis isoformas que sao: MC1R, MC2R, MC3R, MC4R, MC5R e o MC6R, porem somente o MC2R e expresso na glandula adrenal (FLUCK; MILLER, 2008).
Results suggest a localized anti-inflammatory influence based on alpha-MSH and its receptors: duodenal mucosa showed evidence of alpha-MSH and two of its receptor subtypes, MC1R and MC5R.