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MAO-B inhibitors

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MAO-B inhibitors
Inhibitors of the enzyme monoamine oxidase B. MAO-B helps break down dopamine; inhibiting it prolongs the action of dopamine in the brain. Selegiline is an MAO-B inhibitor.
Mentioned in: Parkinson Disease


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1) As such, MAO-B inhibitors prolong the local effects of dopamine at CNS synapses.
7 million) due to increased clinical trials expenses for the development of our pipeline and a significant upfront payment for the acquisition of the MAO-B inhibitors from Roche in Q1.
Neurology 46: 1262-1269 Da Prada M, Kettler R, Keller HH, Cesura AM, Richards JG, Saura Marti J, Muggli-Maniglio D, Wyss PC, Kyburz E, Imhof R (1990) From moclobemide to Ro 19-6327 and Ro 41-1049: the development of a new class of reversible, selective MAO-A and MAO-B inhibitors.
 
 
 
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