MAC awake

MAC awake

end-tidal concentration of an inhaled anesthetic agent at which 50% of patients appropriately respond to verbal commands (such as "open your eyes"). It applies only to inhalation agents and is affected by medical comorbidities, age, hypothermia, narcotic administration and sedatives.

median alveolar concentration awake

The end-tidal concentration of inhaled anaesthetic that prevents appropriate voluntary responses (perceptive awareness) to spoken commands (e.g., to open one’s mouth or to raise a hand) in 50% of a test population.